Portuguese Lopez settled in London in 1559. He was a physician at St Bart's and then to Robert Dudley, Earl of Leicester, before moving into Elizabeth's employ.
In 1584, a Catholic tract attacking Leicester accused Lopez of poisoning, but it wasn't true. However, he made an enemy of Essex after he told Spanish officials details of Essex's health.
The charges against Lopez appear to be false. He maintained his innocence, and the queen seemed unsure of his guilt. It didn't save him, though.
Lopez may have been the inspiration for Shylock in Shakespeare’s "The Merchant of Venice".
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Image: An engraving by Esaias van Hulsen of Roderigo Lopez and a Spaniard plotting to poison Elizabeth I.