Alessandro Farnese was born on 29 February 1468 at Canino, Latium, which was in the Papal States. Educated at the University of Pisa and Lorenzo de Medici’s court, he was prepared to take on the career of apostolic notary. Changing course, Alessandro joined the Roma Curia in 1491 at the age of approximately 23 and was quickly promoted by the new pope Alexander VI to a cardinal-deacon position at Santi Cosma e Damiano two years later. Alessandro had the early makings of a fine career with the church. His family already boasted of Pope Boniface VIII.